Cxbladder is a family of non-invasive molecular diagnostic laboratory tests optimized to help you assess the probability that your patient has bladder cancer, giving you actionable results that can make a meaningful difference in their treatment.

Reliable

More reliable and objective than many other urine-based tests, Cxbladder utilizes high sensitivity and Negative Predictive Value to provide accurate results.1,2

Actionable

Cxbladder provides actionable results to facilitate the early detection of bladder cancer by either helping to rule out the disease or to complement other diagnostic procedures and tests.

Efficient

Non-invasive and pain free, Cxbladder provides a complete sampling system for collection of the patient’s urine sample and shipment to our laboratory.

Credible

Over ten years of research has identified five specific messenger RNA (mRNA) biomarkers that represent a bladder cancer signature.3 Cxbladder has been validated by a multicenter clinical study published in a highly respected peer reviewed journal.

Clinical Applications

Cxbladder gives you actionable results that can make a meaningful difference in your patient's diagnosis and treatment.

  • References

    1 O'Sullivan et al: A multigene urine test for the detection and stratification of bladder cancer in patients presenting with hematuria, J Urol 2012; 188: 741-747

    2 Kavalieris et al: A segregation index combining phenotypic (clinical characteristics) and genotypic (gene expression) biomarkers from a urine sample to triage out patients presenting with hematuria who have a low probability of urothelial carcinoma. BMC Urology 2015; 15:23 Read article

    3 Holyoake et al: Development of a multiplex RNA urine test for the detection and stratification of transitional cell carcinoma of the bladder, Clin Cancer Res 2008; 14(3): 742-749

    Pacific Edge is responsible for the development and determination of the performance characteristics for Cxbladder. Because Cxbladder is a Laboratory Developed Test (LDT), Cxbladder has not been cleared or approved by the US Food and Drug Administration (FDA).

Diagnosing bladder cancer

Drs Sia Daneshmand and Joseph DiTrolio discuss the guidelines, issues and technologies for diagnosing UC in patients presenting with hematuria in primary care.

Diagnosing bladder cancer
Diagnosing bladder cancer