There may be a link between a medicine used to treat diabetes, pioglitazone (Actos®)* and bladder cancer. If you have taken or are now taking pioglitazone, you may be worried about bladder cancer. In this case, we suggest that you talk to your doctor. This is especially important if you are aged 35+ years or you have taken pioglitazone for more than 12 months.

Your doctor may suggest that you have a full urologic assessment. Alternatively, s/he might suggest that you use a Cxbladder test to rule out bladder cancer. This accurate, reliable and pain-free urine test can give you confidence, reassurance and peace of mind.

* In several regions, various generic versions of pioglitazone (Actos) are available.

Pioglitazone and bladder cancer

  • Several studies have identified a strong link between pioglitazone and bladder cancer.
  • In June 2011, the US Food and Drug Administration said that pioglitazone increased the risk of bladder cancer by 40%. This depended on pioglitazone dosage and duration of use.
  • In one study, pioglitazone increased the risk of bladder cancer by 83%.
  • Are you taking pioglitazone? Do you have blood in your urine, regular urgency to urinate, or experience pain when urinating? If so, talk to your doctor immediately.

You should not take pioglitazone if you have active bladder cancer or a history of bladder cancer.

  • Talk to your doctor

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    Are you alarmed about blood in your urine? Worried about bladder cancer? Download our patient discussion guide for a list of questions you can ask your doctor.

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