With Cxbladder you’re in safe hands.

Over 20 years of research has led to the development and evolution of a state-of-the-art test that works at a molecular level, measuring five biomarker genes to help rule out urothelial bladder cancer.

Our research shows that the messenger RNA (mRNA) levels within these five biomarker genes are different in urine from patients with urothelial bladder cancer than those without.1

Only a small mid-stream urine sample is needed for the Cxbladder test. Once it reaches our accredited US laboratory, the urine sample is processed to extract and purify the mRNA present. We then use a technique called Reverse Transcription Quantitative Polymerase Chain Reaction (RT-qPCR) to amplify and measure the biomarker genes of interest.

It’s the quantity of these biomarker genes in relation to each other that we use to calculate our Cxbladder test scores.
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Last Updated: 20 Mar 2024 01:38 pm

  • References

    1 Holyoake A, O’Sullivan P, Pollock R, et al. Development of a multiplex RNA urine test for the detection and stratification of transitional cell carcinoma of the bladder. Clin Cancer Res 2008;14:742–9.

How does Cxbladder work

Find out more about the science behind the test.

How does Cxbladder work
How does Cxbladder work
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    Are you alarmed about blood in your urine? Worried about bladder cancer? Download our patient discussion guide for a list of questions you can ask your doctor.

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